AudiLab research
Introduction
Quantitative modelling of the middle ear
The overall objective of our auditory research is a quantitative
understanding of the mechanical behaviour of the middle ear. The
immediate goal is a good mathematical model of the middle ear using
the ‘finite-element’ method, which depends heavily on the use of
computers. We use the powerful and flexible
finite-element modelling methodology in very close collaboration with
state-of-the-art experimental work in order
to arrive at the comprehensive quantitative framework necessary for a
real understanding of the system.
This research will lead to a solid understanding of how the
eardrum and middle ear behave mechanically. It will provide a
theoretical tool to guide, among other things,
- the design and choice of techniques for middle-ear surgery; and
- the clinical evaluation of middle-ear and inner-ear function.
See lecture notes on
Objectives of middle-ear research for more details.
Our research is done in collaboration
with a number of other groups.
Three-dimensional modelling of complex natural structures
The overall objective of this research is to develop innovative
approaches to the creation of computer-based 3-D models of complex
natural objects, for the purposes of both visualization and
simulation. The emphasis is on the
creation of high-quality finite-element models for complex structures
consisting of multiple heterogeneous substructures.
The techniques developed in this research will be useful in
many research areas besides the middle ear, and also in teaching.
= journal article,
= conference presentation,
= book chapter
See also Complete list of publications
- Gea SLR, Decraemer WF, Funnell WRJ, Dirckx JJJ & Maier H (2010):
Tympanic-membrane boundary conditions derived from static displacements
observed with computerized tomography in human and gerbil.
J Assoc Res Otolaryngol 11(1): 1-17
(Correction)
(doi:10.1007/s10162-009-0192-9)
© 2009 Association for Research in Otolaryngology.
This article may be found at
http://www.springerlink.com/content/l88354k622327033/
- Decraemer WF & Funnell WRJ (2008):
Anatomical and mechanical properties of the tympanic membrane.
Pp. 51-84 in Chronic otitis media: Pathogenesis-oriented
therapeutic management, B. Ars (ed.), Kugler, The Hague
©
2008 Kugler Publications, The Hague, Amsterdam, The Netherlands.
-
Audette M, Brooks R, Funnell WRJ, Strauss G & Arbel T (2008):
Piecewise affine initialized spline-based patient-specific registration
of a high-resolution ear model for surgical guidance.
MICCAI Workshop on Image Guidance and Computer Assistance
for Soft-Tissue Interventions, New York, 1-10
(Conference Web site)
-
Qi L, Funnell WRJ & Daniel SJ (2008):
A nonlinear finite-element model of the newborn middle ear.
J Acoust Soc Am 124(1): 337-347
(doi:10.1121/1.2920956)
© 2008 Acoustical Society of America.
This article may be downloaded for personal use only. Any other use
requires prior permission of the author and the Acoustical Society of
America. The article may be found at
http://link.aip.org/link/?JAS/124/337
- Nambiar S, Chakravarty MM & Funnell WRJ (2008):
Non-linear registration of serial histological images of the middle ear.
Proc 31st Ann Conf Can Med Biol Eng Soc,
paper A9.3, 3 pp. (CD-ROM)
- Akache F, Funnell WRJ & Daniel SJ (2007):
An experimental study of tympanic membrane and
manubrium vibrations in rats.
Audiol Neurotol 12(1): 49-58
(doi:10.1159/000097247)
© 2007 S. Karger AG, Basel.
This article may not be used for commercial purposes.
The article may be found at
http://dx.doi.org/10.1159/000097247
-
Qi L, Liu H, Lutfy J, Funnell WRJ & Daniel S (2006):
A nonlinear finite-element model of the newborn ear canal.
J Acoust Soc Am 120: 3789-3798
(doi:10.1121/1.2363944)
© 2006 Acoustical Society of America.
This article may be downloaded for personal use only. Any other use
requires prior permission of the author and the Acoustical Society of
America. The article may be found at
http://link.aip.org/link/?JAS/120/3789
- Elkhouri N, Liu H & Funnell WRJ (2006):
Low-frequency finite-element modeling
of the gerbil middle ear.
JARO 7: 399-411
(doi:10.1007/s10162-006-0055-6)
© 2006 Association for Research in Otolaryngology.
This article may be found at
http://www.springerlink.com/content/d1378524t4544164/
- Funnell WRJ & Maysinger D (2006):
Three-dimensional reconstruction of cell nuclei,
internalized quantum dots and sites of lipid peroxidation.
J Nanobiotechnology 4: 10, 19 pp.
(local copy of PDF file)
-
Nicholson DT, Chalk C, Funnell WRJ & Daniel SJ (2006):
A randomized controlled study of a computer-generated
three-dimensional model for teaching ear anatomy.
Medical Education 40: 1081-1087
(doi:10.1111/j.1365-2929.2006.02611.x)
See also follow-up letter: The evidence for virtual reality.
Medical Education 42: 224, 2008
(doi:10.1111/j.1365-2923.2007.02982.x)
© 2006 Blackwell Publishing Ltd.
This article may not be used for commercial purposes.
- Ladak HM, Funnell WRJ, Decraemer WF & Dirckx JJJ (2006):
A geometrically nonlinear finite-element model
of the cat eardrum.
J Acoust Soc Am 119: 2859-2868
(doi:10.1121/1.2188370)
© 2006 Acoustical Society of America.
This article may be downloaded for personal use only. Any other use
requires prior permission of the author and the Acoustical Society of
America. The article may be found at
http://link.aip.org/link/?JAS/119/2859
- Funnell WRJ, Daniel SJ, Alsabah B & Liu H (2005):
On the coupling between the incus and the stapes.
Auditory mechanisms: processes and models,
Proc. Ninth International Mechanics of Hearing Workshop,
Portland (OR)
-
Funnell WRJ, Siah TH, McKee MD, Daniel SJ & Decraemer WF (2005):
On the coupling between the incus and the stapes in the cat.
JARO 6(1): 9-18
(doi:10.1007/s10162-004-5016-3)
© 2005 Association for Research in Otolaryngology.
This article may be found at
http://www.springerlink.com/content/ujwxgf17vd33qty3/
- Hagr AA, Funnell WRJ, Zeitouni AG & Rappaport JM (2004):
High-resolution x-ray computed tomographic scanning
of the human stapes footplate.
J. Otolaryngol. 33(4): 217-221
[preprint; version with better
quality images, ~225 kB]
- Qi L & Funnell WRJ (2004):
Compression Effects of JPEG and JPEG2000 on Temporal-Bone Images.
Proc 28th Ann Conf Can Med Biol Eng Soc, 71-74
- Akache F, Daniel SJ & Funnell WRJ (2004):
An experimental study of middle-ear vibrations in rats.
Proc 28th Ann Conf Can Med Biol Eng Soc, 114-117
- Mikhael CS, Funnell WRJ & Bance M (2004):
Middle-ear finite-element modelling with realistic geometry and
a priori material-property estimates.
Proc 28th Ann Conf Can Med Biol Eng Soc, 126-129
- Qi L, Mikhael CS & Funnell WRJ (2004):
Application of the Taguchi method to sensitivity analysis
of a middle-ear finite-element model.
Proc 28th Ann Conf Can Med Biol Eng Soc, 153-156
- Qi L, Mikhael CS & Funnell WRJ (2004):
Application of the Taguchi method to middle-ear
finite-element modelling.
27th Midwinter Res. Mtg.,
Assoc. Res. Otolaryngol., Daytona Beach
[version with better
quality images, ~1.5 MB]
- Decraemer WF, Dirckx JJJ & Funnell WRJ (2003):
Three-dimensional modelling of the middle-ear ossicular chain
using a commercial high-resolution x-ray CT scanner.
JARO 4(2): 250-263
(doi:10.1007/s10162-004-5016-3)
© 2003 Association for Research in Otolaryngology.
This article may be found at
http://www.springerlink.com/content/1btnfu60hx727bmq/
- Funnell WRJ, Siah TH, McKee MD,
Daniel SJ & Decraemer WF (2003):
On the coupling between the incus and the stapes
in the cat.
26th Midwinter Res. Mtg.,
Assoc. Res. Otolaryngol., Daytona Beach
[version with better
quality images, ~11 MB]
- Funnell WRJ (2002):
Finite-element modelling of nonlinear behaviour
of the middle ear. Part of Workshop
on Static pressure in the middle ear,
25th Midwinter Res. Mtg.,
Assoc. Res. Otolaryngol., St. Petersburg Beach (invited)
[Same as presented at conference by Wim Decraemer in my absence,
except that one new figure and some textual revisions didn't
make it into the presented version, and the animations didn't work]
- Funnell WRJ (2001):
High-frequency time-domain behaviour of a finite-element model
of the eardrum.
24th Midwinter Res. Mtg.,
Assoc. Res. Otolaryngol., St. Petersburg Beach
[Same as presented at conference except for addition of
three missing references]
- Funnell WRJ, Decraemer WF, von Unge M & Dirckx JJJ (2000):
Finite-element modelling of the gerbil eardrum and middle ear.
23rd Midwinter Res. Mtg.,
Assoc. Res. Otolaryngol., St. Petersburg Beach
- Funnell WRJ, Decraemer WF, von Unge M & Dirckx JJJ (1999):
Finite-element modelling of the gerbil eardrum and middle ear.
22nd Midwinter Res. Mtg.,
Assoc. Res. Otolaryngol., St. Petersburg Beach
- Funnell WRJ, Decraemer WF & Khanna SM (1997):
Damped vibration patterns on a finite-element model
of the cat eardrum.
22nd Midwinter Res. Mtg.,
Assoc. Res. Otolaryngol., St. Petersburg Beach
-
Decraemer WF, Khanna SM & Funnell WRJ (1997):
Vibrations of the cat tympanic membrane measured with high spatial resolution.
22nd Midwinter Res. Mtg.,
Assoc. Res. Otolaryngol., St. Petersburg Beach
- Funnell WRJ (1996):
Finite-element modelling of the cat middle ear
with elastically suspended malleus and incus.
19th Midwinter Res. Mtg.,
Assoc. Res. Otolaryngol., St. Petersburg Beach
-
Ladak HM & Funnell WRJ (1996):
Finite-element modeling of the normal and surgically repaired
cat middle ear.
J. Acoust. Soc. Am. 100(2): 933-944
(doi:10.1121/1.416205)
© 1996 Acoustical Society of America.
This article may be downloaded for personal use only. Any other use
requires prior permission of the author and the Acoustical Society of
America. The article may be found at
http://link.aip.org/link/?JAS/100/933
-
Funnell WRJ & Decraemer WF (1996):
On the incorporation of moiré shape measurements
in finite-element models of the cat eardrum.
J. Acoust. Soc. Am. 100(2): 925-932
(doi:10.1121/1.416252)
© 1996 Acoustical Society of America.
This article may be downloaded for personal use only. Any other use
requires prior permission of the author and the Acoustical Society of
America. The article may be found at
http://link.aip.org/link/?JAS/100/925
- Funnell WRJ (1996):
Low-frequency coupling between eardrum and manubrium
in a finite-element model.
J. Acoust. Soc. Am. 99(5): 3036-3043
(doi:10.1121/1.414875)
© 1996 Acoustical Society of America.
This article may be downloaded for personal use only. Any other use
requires prior permission of the author and the Acoustical Society of
America. The article may be found at
http://link.aip.org/link/?JAS/99/3036
- Ghosh SS & Funnell WRJ(1995):
On the effects of incudostapedial joint flexibility
in a finite-element model of the cat middle ear.
Proc. IEEE EMBS 17th Annual Conference &
21st Can. Med. & Biol. Eng. Conf., Montréal: 1437-1438
-
Funnell WRJ, Khanna SM & Decraemer WF (1992):
On the degree of rigidity of the manubrium
in a finite-element model of the cat eardrum.
J. Acoust. Soc. Am. 91(4): 2082-2090
(doi:10.1121/1.403694)
© 1992 Acoustical Society of America.
This article may be downloaded for personal use only. Any other use
requires prior permission of the author and the Acoustical Society of
America. The article may be found at
http://link.aip.org/link/?JAS/91/2082
-
Funnell WRJ, Decraemer WF & Khanna SM (1987):
On the damped frequency response of a finite-element model of the
cat eardrum.
J. Acoust. Soc. Am. 81(6): 1851-1859
(doi:10.1121/1.394749)
© 1987 Acoustical Society of America.
This article may be downloaded for personal use only. Any other use
requires prior permission of the author and the Acoustical Society of
America. The article may be found at
http://link.aip.org/link/?JAS/81/1851
- Funnell WRJ (1984):
On the choice of a cost function
for the reconstruction of surfaces
by triangulation between contours.
Computers & Structures
18(1): 23-26
- Funnell WRJ & Laszlo CA (1982):
A critical review of experimental observations
on eardrum structure and function.
ORL 44(4): 181-205
[The extensive list of references
was not printed with the paper because of lack of space.]
-
Funnell WRJ & Laszlo CA (1978):
Modelling of the cat eardrum as a thin shell
using the finite-element method.
J. Acoust. Soc. Am. 63(5): 1461-1467
(doi:10.1121/1.381892)
© 1978 Acoustical Society of America.
This article may be downloaded for personal use only. Any other use
requires prior permission of the author and the Acoustical Society of
America. The article may be found at
http://link.aip.org/link/?JAS/63/1461
Note:
The Web versions of most of these documents were automatically converted
from the original format. The articles correspond to the final manuscripts and
do not include the journals' editorial changes.
Figures are not included, and
special symbols, e.g., the Greek character pi,
are mostly missing.
AudiLab home page
R. Funnell
Last modified: 2012-02-07 07:17:53